shERWOOD shRNA Design + Optimized shRNA Processing = Superior Knockdown
shERWOOD-UltramiR shRNA Reagents Next generation vector-based RNAi triggers designed using the proprietary shERWOOD algorithm developed and validated in Dr. Gregory Hannon’s laboratory at Cold Spring Harbor Laboratory (Knott et al 2014). An alternate microRNA scaffold “UltramiR” has been optimized for increased shRNA processing and potency based on new information on the key determinants for primary microRNA processing (Auyeung et al 2013).
Sensor-based shRNA-mir constructs for performing RNAi in primary and non-dividing cells.
- shERWOOD algorithm designs ensure more efficient shRNA-mir processing and potency at single copy
- microRNA-30 context increases knockdown specificity and reduces toxicity
- All shRNA-mir designs are scored and ranked per gene
- 100% Guaranteed Knockdown
shERWOOD UltramiR Pooled Screening Libraries Choice of promoter, reporter, gene content and more
Achieve superior RNAi screens with enhanced potency, sequence-verified shRNA pools and flexible delivery strategies.
|Greater confidence in your results||
|Choose the best promoter for your cells||
|Your choice of format||
|Pool Deconvolution Service||
To view more product information, see Transomic Technologies