Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life.

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Image Variation SKU Price Quantity Add To Cart
BSEP-IHC518-Liver 0.1ml IHC518-100 671.00
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BSEP-IHC518-Liver 1ml IHC518-1 3,484.00
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BSEP-IHC518-Liver Positive Control 3 slides IHC518-PC 1,323.00
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CE-IVD registered and supplied as a concentrate.   


Clone IHC518
Source Mouse Monoclonal
Positive Control Liver
Dilution Range 1:100 – 1:200


    1. Strautnieks S, et al. Nature Genetics. 1998; 20:233–8.
    2. Noé J, et al. Gastroenterology. 2002; 123:1659–66.
    3. Arrese M, et al. Pflügers Archiv. 2004; 449:123–31.
    4. Jansen PL, et al. Gastroenterology. 1999; 117:1370–9.
    5. van Mil SW, et al. Gastroenterology. 2004; 127:379–84.
    6. Knisely AS, et al. Hepatology. 2006; 44:478–86.





Additional information


0.1ml, 1ml, Positive Control 3 slides


Instructions for Use

Safety Data Sheet

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