Cluster of differentiation 57 (CD57), also known as NK-1, is an antigen detectable in natural killer cells, some T-lymphocytes and normal peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides, lipids, and chondroitin sulfate proteoglycans. CD57 is indicated as a marker for tumors of neuroendocrine origin, including pheochromocytomas, paragangliomas, carcinoid tumor, and medulloblastomas, as well as various neural tumors including neuromas, neurofibromas, schwannomas, and granular cell tumors. CD57 is also detectable in ganglioneuroma and prostate carcinoma. Anti-CD57 is used to distinguish nodular lymphocyte-predominant Hodgkin’s lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis Hodgkin’s disease, and follicular lymphoma.

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Image Variation SKU Price Quantity Add To Cart
CD57-IHC539-Tonsil 0.1ml IHC539-100 231.00
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CD57-IHC539-Tonsil 1ml IHC539-1 754.00
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CD57-IHC539-Tonsil Positive Control 3 slides IHC539-PC 553.00
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CE-IVD registered and supplied as a concentrate.   


Clone IHC539
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 – 1:200


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  6. Khoury T, et al. Int J Exp Pathol. 2011; 92:87-96.
  7. Boudova L, et al. Blood. 2003; 102:3753-8.
  8. Dabbs DJ. 2014: 324.
  9. Eiden SV, et al. Hum Pathol. 2002; 33:1126-32.

Additional information


0.1ml, 1ml, Positive Control 3 slides


Instructions for Use

Safety Data Sheet

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