p53
p53
₪231.00 – ₪936.00
p53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.
| Image | Variation | SKU | Price | Quantity | Add To Cart |
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0.1ml | IHC053-100 | ₪231.00 | |
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1ml | IHC053-1 | ₪936.00 | |
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Positive Control | IHC053-PC | ₪553.00 | |
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Description
CE-IVD registered and supplied as a concentrate.
Specifications
| Clone | IHC053 |
| Source | Mouse Monoclonal |
| Positive Control | Colon Carcinoma |
| Dilution Range | 1:100 – 1:200 |
References
- Stoehlmacker J, et al. Oncol. 2003; 30:10-16.
- Gallo O, et al. Hum Pathol. 2002; 33:708-714.
- Sano H, et al. Cancer Res. 1995: 55:3785-9.
- Denkert C, et al. Cancer. 2003; 97:2978-87.
- Sheehan KM, et al. Hum Pathol. 2003; 34:1242-1246.
- Moore BE, et al. Appl Immunohistochem Mol Morphol. 2001; 9:203-6.
- Mauri FA, et al. Int J Oncol. 1999; 15:1137-47.
- Caffo O, et al. Clin Cancer Res. 1996; 2:1591-9.
- Bebenek M, et al. Anticancer Res. 1998; 18:619-23.
- Midulla C, et al. Anticancer Res. 1999; 19:4033-7.
- Zen ZS, et al. J Clin Oncol. 1994; 12:2043-50.
- Quinlan DC, et al. Cancer Res. 1992; 53:4828-31.
- Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.
Additional information
| Unit | 0.1ml, 1ml, Positive Control |
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