p53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.

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Image Variation SKU Price Quantity Add To Cart
p53-IHC053-Colon-Cancer 0.1ml IHC053-100 231.00
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p53-IHC053-Colon-Cancer 1ml IHC053-1 936.00
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p53-IHC053-Colon-Cancer Positive Control IHC053-PC 553.00
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CE-IVD registered and supplied as a concentrate.


Clone IHC053
Source Mouse Monoclonal
Positive Control Colon Carcinoma
Dilution Range 1:100 – 1:200


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  6. Moore BE, et al. Appl Immunohistochem Mol Morphol. 2001; 9:203-6.
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  8. Caffo O, et al. Clin Cancer Res. 1996; 2:1591-9.
  9. Bebenek M, et al. Anticancer Res. 1998; 18:619-23.
  10. Midulla C, et al. Anticancer Res. 1999; 19:4033-7.
  11. Zen ZS, et al. J Clin Oncol. 1994; 12:2043-50.
  12. Quinlan DC, et al. Cancer Res. 1992; 53:4828-31.
  13. Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.

Additional information


0.1ml, 1ml, Positive Control


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