Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability, and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Expression levels of the PMS2 protein may be useful as a screening tool for Lynch syndrome after a colorectal cancer diagnosis. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MLH1, MSH2, and MSH6.

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Image Variation SKU Price Quantity Add To Cart
PMS2-IHC412-Duodenum 0.1ml IHC412-100 532.00
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PMS2-IHC412-Duodenum 1ml IHC412-1 2,600.00
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PMS2-IHC412-Duodenum Positive Control IHC412-PC 770.00
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CE-IVD registered and supplied as a concentrate.   


Clone IHC412
Source Mouse Monoclonal
Positive Control Colon
Dilution Range 1:100 – 1:200


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  12. Gill S, et al. Clin Cancer Res. 2005; 11:6466-71.
  13. Modica I, et al. Am J Surg Pathol. 2007; 31:744-51.
  14. Shia J, et al. Am J Surg Pathol. 2009; 33:1639-45.
  15. Kets CM, et al. Mod Pathol. 2006; 19:1624-30.

Additional information


0.1ml, 1ml, Positive Control


Instructions for Use

Safety Data Sheet

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