Sal-Like Protein 4 (SALL4), is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumors (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germ-cell tumors, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.

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Image Variation SKU Price Quantity Add To Cart
SALL4-IHC659-Testicular-Cancer 0.1ml IHC659-100 278.00
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SALL4-IHC659-Testicular-Cancer 1ml IHC659-1 1,196.00
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SALL4-IHC659-Testicular-Cancer Positive Control IHC659-PC 770.00
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CE-IVD registered and supplied as a concentrate.


Clone IHC659
Source Mouse Monoclonal
Positive Control Seminoma, Dysgerminoma
Dilution Range 1:100 – 1:200


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  4. Miettinen M, et al. Am J Surg Pathol. 2014; 38:410–20.
  5. Zhang X, et al. Cancer Lett. 2015; 357:55–62.
  6. Ueno S, et al. Exp Hematol. 2014; 42:307–16.
  7. Cao D, et al. Am J Surg Pathol. 2009; 33:1065–77.
  8. Zhang L, et al. Oncogene. 2014; 33:5491–500.
  9. Kobayashi D, et al. Int J Oncol. 2011; 38:933–9.
  10. Cui W, et. al. Mod Pathol. 2006; 19:1585-92.
  11. Cao D, et al. Am J Surg Pathol. 2009; 33:894-904.

Additional information


0.1ml, 1ml, Positive Control


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