SOX-10
SOX-10
₪463.00 – ₪2,158.00
SRY (Sex Determining Region Y)-Box 10 (SOX-10), also known as transcription factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.
| Image | Variation | SKU | Price | Quantity | Add To Cart |
|---|---|---|---|---|---|
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0.1ml | ₪463.00 |
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Add to cart | |
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1ml | ₪2,158.00 |
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Add to cart | |
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Positive Control | ₪962.00 |
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Add to cart |
Description
CE-IVD registered and supplied as a concentrate.
Specifications
| Clone | IHC010 |
| Source | Mouse Monoclonal |
| Positive Control | Melanoma, Skin Melanocytes |
| Dilution Range | 1:100 – 1:200 |
References
- Pingault V, et al. Nat Genet. 1998; 18:171-3.
- Bondurand N, et al. Hum Mol Genet. 2000; 8:1785-9.
- Kelsch RN. BioEssays. 2006; 28:788.
- Nonaka D, et al. Am J Surg Pathol. 2008; 32:1291-8.
- Chorny JA, et al. Am J Dermatopathol. 2002; 24:309-12.
- Robson A, et al. Histopathology. 2001; 38:135-40.
- Longacre T, et al. Am J Surg Pathol. 1996; 20:1489-500.
- Ramos-Herberth FI, et al. J Cutan Pathol. 2010; 37:944–52.
Additional information
| Unit | 0.1ml, 1ml, Positive Control |
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